A ready-to-use monolayer cell-based assay for MDR1 in-vitro evaluation of drug interactions with the P-gp/MDR1 transporter. The assay is suitable for performing both inhibition and substrate assessments. The kit consists of 24- or 96-well permeable plates seeded with differentiated MDCKII cells expressing MDR1 as well as the parental cell line.
Benefits
- Differentiated MDCKII-MDR1 cell barrier (11 day system) plated on HTS Transwell®-24 and -96 permeable supports.
- Integrated Transwells enable easy handling and provide a user-friendly system.
- Proprietary conditioning medium allows for up to 11 days of transportation/storage at room temperature.
- Adaptable to automation.
- Cost-effective for any size laboratory.
Product Information
| Product Number | Product Name | Format |
|---|
| 001-1004 |
PreadyPort-MDR1 (MDCKII-MDR01) Kit |
24-well plate |
| 001-1005 |
PreadyPort-MDR1 (MDCKII-MDR01) Kit |
96-well plate |
| 001-1006 |
PreadyPort-CTRL (MDCKII Cells Parental [CTRL]) Kit |
24-well plate |
| 001-1007 |
PreadyPort-CTRL (MDCKII Cells Parental [CTRL]) Kit |
96-well plate |
| 001-1008 |
PreadyPort-MDR1/CTRL (MDCKII Cell-Based Assay, 50% MDR1[CTRL]) Kit |
24-well plate |
| 001-1009 |
PreadyPort-MDR1/CTRL (MDCKII Cell-Based Assay, 50% MDR1[CTRL]) Kit |
96-well plate |
PreadyPort™ is a registered trademark of Solvo Biotechnologies and ReadyCell/Advancell