A fast high throughput Brain Absorption and Protein Binding assay for brain tissue binding, plasma proteins binding and brain disposition. The assay estimates the binding of drugs to brain tissue as well as to human plasma proteins. It also predicts the disposition of drugs into the brain.

Benefits

• Ready-to-use 96-well microtiter plates carrying TRANSIL beads with a single lipid bilayer reconstituted from porcine brain lipids and physiological mixture of immobilized human serum albumin and a1-acid glycoprotein, designed to conveniently measure brain tissue binding, plasma proteins binding and predict drugs disposition into the brain.
• TRANSIL beads integrated into 96-well microtiter plates enable easy handling.
• One plate can be used for measuring brain tissue binding, plasma proteins binding and brain disposition of up to 8 compounds.
• Only 12 minutes assay incubation time.
• Kit includes spreadsheet, facilitating manipulation of statistical parameters and calculation of final results.
• Highly reproducible results, and robust correlation with conventional dialysis technique.
• Designed for automated liquid handlers.

Product Information

TRANSIL^® is a trademark of Sovicell.