A novel plasma protein binding assay for sticky and tightly bound compounds. The assay accurately predicts the free fraction of the drugs in plasma, even if the fraction is below 1%. It is designed to accurately determine the free fraction of highly lypophilic drugs or any other compounds that tend to tightly bind to dialysis tubing or other surfaces.

Benefits

• Ready-to-use silanized glass vials pre-filled with buffer and membrane beads, designed to conveniently assess plasma protein binding of compounds through competitive binding to cell membrane on the beads.
• Accurate detection of very low free fractions (=1%).
• High recovery even with very sticky compounds.
• Versatile assay that can be used with plasma from various species (i.e; human, monkey, dog, rat and mouse).
• User friendly and easy handling system.
• Only 30 minutes assay incubation time.
• Kit includes spreadsheet, facilitating manipulation of statistical parameters and calculation of final results.

Product Information

TRANSIL^® is a trademark of Sovicell.