Accelerate Your Drug Development Processes By Using Ready To Use Assays

Posted by Sandy Koshkin on Wed, Jul 27, 2011 @ 05:31 PM

Accelerate Your Drug Discovery and Development Processes and Control  Your Data when Evaluating New Drug Compounds by Using Ready-to-Use Assays

State of the art Ready-to-Use Assays-  offered by ADMEcell www.admecell.com eliminate the need for time consuming in-house reagent preparations and assay development, thereby reducing the costs and enhancing the drug discovery and development processes.  ADMEcell’s CacoReady  and PreadyPort-MDR1 Ready To Use ELISA Kitshttp://www.admecell.com/assays-cellbased/ are examples of Ready-to-Use Assay Kits  for generating  permeability data for new drug candidates.  These assays eliminate the need for in-house cell culture production offering  a great deal of cost  and time savings. In addition, you will have control on generating your own data without delays.   ADMEcell also offers a number of Ready-to-Use products with the same benefits for the assessment of Plasma Protein Binding and Blood Brain Absorption of drug candidates http://www.admecell.com/assays-transil/ Finally, ADMEcell ELISA-Based Ready-to-Use Assay Kits http://www.admecell.com/assays-elisabased/ for quantification of IgG from various species and Mouse Ig Isotyping are available for rapidly and conveniently screening of therapeutic antibodies.

Once a biotech company has decided to implement this strategy,  application of the Ready-to-Use Assay Kits will surely become an important part of its long term preclinical development plan.

Tags: ELISA Kits, Human IgG Kits, Mouse IgG Kits, Ready To Use Assays, Ready To Use Kits, MDR1 Kits, Protein Binding Kits, Blood Brain Absorption Kits, Caco-2 Kits, Caco-2 Assays

Overview of the Cell Based Assays Market

Posted by Sandy Koshkin on Wed, Jul 20, 2011 @ 01:32 PM

Cell Based AssaysThe increasing need to predict ADME/TOX profiles has led to development of new technologies among which cell based assays are one of the most effective  techniques used in almost every phase of drug discovery and development. They are used to study the  molecular interactions in a cellular environment and are crucial in compound selections, lead generations,optimization and screening. Cell based assays provide details such as permeability, metabolism, selectivity, combination and most importantly- a toxicity profile. 

Cell Based Assays based on measuring transporters across membranes Csuch as Caco-2 and MDR1 assays (to mention a few) are among established methods that are utilized for IND submission for new compounds. The FDA has a list of the necessary studies for transporters.

The market for cell based assays is approaching a billion dollars annually, worldwide with at least a 10% yearly growth rate.  Currently, in-house developed assays and CROs are responsible for almost all of the business.

Recently, in vitro assays marketed as Ready-to-Use kits have gained popularity and are becoming more important as biotech and Pharma industries are focused on saving costs of in-house cell culture production and assay development as well as result turnaround time.

Cell based assays based on Ready-to-Use products concept are cost effective, convenient and do not require the end user to maintain a costly and tedious cell culture facility.

ADMEcell's Ready-To-Use Cell Based Assay:

 *CacoReady: http://www.admecell.com/cacoready.html?prodid=1 and related products:  http://www.admecell.com/assays_cellbased.html – State of the art cell-based assays, providing ease of use and a cost effective in-vitro technology for evaluation of oral absorption efficiency, compound screening, oral bioavailability, mechanisms of oral/intestinal absorption, oral toxicity and transporter studies – all without in-house cell line development, acquisition or propagation;

Tags: cell based assays

First ADMEcell Blog

Posted by Sandy Koshkin on Tue, Jul 05, 2011 @ 08:56 PM

Welcome to the ADMEcell Blog. As part of our efforts to keep you updated on new developments at ADMEcell, we will be updating this space with product news and special offers from our Executive and Sales teams and new findings, technological news and “Posts from the Bench” from our Lab staff.

ADMEcell, Inc., a life science Company located in the San Francisco Bay Area, was established in October 2008 to develop and market unique and proprietary Ready-to-Use Products that accelerate drug discovery and development processes. The ADMEcell management team combines many years of solid experience in product research, development and marketing in diverse areas of biotechnology, including Molecular Diagnostics, Infectious Diseases, Oncology and Immunodiagnostics.  For more details on the management team’s experience and background, please visit: http://www.admecell.com/management.html

ADMEcell’s Ready-to-Use product line includes three major categories:

*CacoReady: http://www.admecell.com/cacoready.html?prodid=1 and related products:  http://www.admecell.com/assays_cellbased.html – State of the art cell-based assays, providing ease of use and a cost effective in-vitro technology for evaluation of oral absorption efficiency, compound screening, oral bioavailability, mechanisms of oral/intestinal absorption, oral toxicity and transporter studies – all without in-house cell line development, acquisition or propagation;

*TRANSIL Brain Absorption, Intestinal Absorption and Plasma Protein Binding products: http://www.admecell.com/assays_transil.html – Fast and high-throughput assays for brain tissue binding, brain disposition and plasma protein binding of compounds (including very sticky and tightly bound compounds);

*FastELYSA Antibody Screening products:  http://www.admecell.com/assays_elisabased.html – Fast and simple ELISA-based assays for quantification of immunoglobulin G from human and other species, screening of high producing clones, monitoring antibody production, transient transfection and characterization of mouse monoclonal isotypes.

You can always follow us on Twitter @ADMEcell or visit our Facebook page at: http://www.facebook.com/pages/ADMEcell/109021822505525 for the latest updates on our technology and products. Visit our main website at www.admecell.com or send us an e-mail at info@admecell.com

The ADMEcell Management Team 

Tags: transporters, caco-2 assay, cell based assays